MGY377H1 Lecture Notes - Lecture 14: Dideoxynucleotide, Sulfate Adenylyltransferase, Base Pair

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Note: slides that were skipped means that the prof just read off of them and didn"t add anything new. A. cytoplasm with spores have 1/3 of the water content than vegetative cells and that confers heat resitance. C is incorrect as there are decreased pg cross linkages in the spore. C. antimicrobial peptides can target various cell processes such as cell wall synthesis for instance. How it is that we actually sequence a bacterial genome. Three major revolutions of microbiology: the germ theory of disease, antibiotics were discovered (anti-microbial resistance), genomics. There are 10x more microbial cells than our own cells. In order to look at the genome, we need to use sequencing. This technology was first developed in the mid 1970s and was rapidly applied to sequence the first bacteriophage (contained an rna genome) Took about 20 years until we could sequence our first cellular genome.

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