PHAR 100 Lecture Notes - Postpartum Bleeding, Reserpine, Psilocybin

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Amazon arrow poison natives dipped their arrow tips into a poison, curare, which caused paralysis by inhibiting ach at the neuromuscular junction blocks muscle contraction derivatives of curare are used today in surgery as a muscle relaxant. : fungus on rye (usually) produces alkaloids usually during wet seasons plant disease e rgot which can produce toxicities in humans. Paracelsus: considered the father of toxicology: all substances are poisons, there is none which is not a poison, the right dose differentiates a poison and a remedy. Early chinese medicine early record of testing: in 2700 bc shen nong classified drugs (botanicals and animal products) according to taste. Early egyptian medicine believed milk from a mother that gave birth to healthy child would cure a sick child: milk was collected and an incantation said over the milk, then administered to sick child.

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