PHAR 100 Lecture Notes - Hypercalcaemia, Gout, Inotrope

• School: Queen's University
• Department: Pharmacology and Toxicology
• Course: PHAR 100
• Professor: Hisham Elbatarny

Document Summary

Normal bp systolic bp (sbp) = heart in contraction ranges between 90 to 140. Arterial (medium sized) blood pressure diastolic bp (dbp) = heart in relaxation ranges between 60 to 90. Renin enzyme released by kidney when blood pressure drops. Which is then converted into angiotensin ii, which is helped by the angiotensin-converting enzyme (ace) Angiotensin ii: causes vasoconstriction, stimulates adrenal gland to release aldosterone: causes salt and water retention, stimulates release of anti-diuretic hormone (adh): causes water retension. Problem: overstimulation of this system hypertension. High blood pressure hypertension: need to do multiple measurements at different times to confirm hypertension: pb > 140 / 90 classification of hypertension: Risk factors of hypertension non-controllable: age, male sex, family history controllable: obesity, physical inactivity, smoking. Diagnosis of hypertension usually asymptomatic (no symptoms) based on measuring bp complications: stroke, heart disease, renal damage, retinal damage.