BIOL 205 Lecture Notes - Pseudoachondroplasia, Cystic Fibrosis, Null Allele
8 Nov 2013
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Figure 2-15 correction n= polidy (number of chromosomes) c= content of dna. Figure 2-15 says 4n but should be 4c to be more correct. What patterns in a pedigree would reveal autosomal recessive inheritance? (1) generally the disorder appears in the progeny of unaffected parents and (2) the affected progeny include both males and females. Affected person in each generation: usually dominant a/a a/a a/a a/a a/a a/a a/a a/a a/a a/a a/a a/a a/a. What patterns in a pedigree would reveal autosomal dominant inheritance? (1) the phenotype tends to appear in every generation of the pedigree. Parents of affected children show the phenotype. (2) half the offspring affected (3) affected fathers or mothers transmit the phenotype to both sons and daughters. pseudoachondroplasia examples: Behaves similar to the mouse t (t-box) mutation. In regards to height: d allele is dominant. In regards to living: d allele is recessive (two copies.
