BIOL 205 Lecture Notes - Thomas Hunt Morgan, William Bateson, Karyotype

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In diploids, recombinants are best detected in a testcross. If the two genes were on the same chromosome. Was mendel correct? early 1900s: william bateson + r. c. Punnett studying inheritance of two factors (genes) in peas they carried out standard f1 dihybrid self crosses but it did not show the. If fused, would predict find telomere sequences in middle, and two centromere regions. Physical maps are known for most genetic model organisms. Thomas hunt morgan studying two autosomal recessive genes in drosophila proposed linkage as a hypothesis to explain the phenomenon of apparent allele association. Eye color: pr = mutant purple pr+= wild-type or red. Wing length: vg = mutant vestigial vg+= wild-type or normal. Now let"s look at another cross that morgan made with the use of the same alleles but in a different combination. Dihybrid testcross results like those just presented are commonly encountered in genetics.

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