ENH 220 Chapter Notes -Coronary Artery Disease, Coronary Circulation, Collateral Circulation

• School: Ryerson University
• Department: Environmental Health
• Course: ENH 220
• Professor: Connie Barbour

Document Summary

Cardiovascular disease is the major cause of death in canada accounting for 29% of all deaths. C-protein (crp) which is produced by the liver, is a nonspecific marker of inflammation the level of. Crp rises with systemic inflammation and is increased in many patients with cad chronic elevations of. Crp are associated with unstable plaques and oxidation of low-density lipoprotein (ldl) cholesterol, leading to increased uptake by the macrophages in the lining macrophages. Fatty streaks: the earliest lesions of atherosclerosis, are characterized by lipid-filled smooth muscle cells. As streaks of fat develop within the smooth muscle cells, a yellow tinge appears treatment that lowers ldl cholesterol may reverse this process. Tobacco use, elevated blood levels of apolipoprotein b or a-1, history of hypertension, dm, abdominal obesity, psychological factors, lack of fruit and vegtable intake, alcohol consumption and physical inactivity. Cardiac risk factors are catergorized as nonmodifable and modifiable. Non-modifiable risk factors: include age, gender, family history, ethinicty, and genetic inheritance.