PHAR 100 Study Guide - Midterm Guide: Muscle Relaxant, Nicotinic Acetylcholine Receptor, Sympathetic Nervous System
21 Nov 2013
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Drugs barely altered, instead me-too drugs created to benefit large companies instead of moving drugs forward (over 57$ billion used in marketing) Mds enticed to prescribe drugs; an example where pfizer had to pay a fine of 2 billion because they promoted drugs where they were not approved through wining and dining with physicians. Ethics: doctors prescribe medicine and consumer has little to no say in what they must take. Therefore, the healthcare professional should make informed, correct decisions. Advertising techniques: catch attention, authorities to endorse product, fear, easy solution to problem, before/after techniques. Miracle drugs showing they can solve any problems perhaps problems that may not even exist (problem child for example) Two experiences led to improved regulations: sulfonamide with toxic solvent which led to deaths and thalidomide which was found to be a teratogenic later on but given during pregnancy. Phase i one or two doses in healthy volunteers (absorption, distribution, elimination and adverse effects (limited)
