BIO203H5 Lecture Notes - Lecture 11: Pyruvate Dehydrogenase, Acetyl-Coa, Oxidative Phosphorylation

38 views11 pages

skykoala223

1 Dec 2013

School

Department

Course

Professor

For unlimited access to Class Notes, a Class+ subscription is required.

Document Summary

Electrochemical gradient produced by the etc forces movement of protons back across the membrane. Atp synthase in membrane uses this energy to phosphorylate adp to form atp. Atp is produced by the enzyme catalyzed transfer of a phosphate group from an intermediate substrate to adp. Substrate level phosphorylation and free energy changes as glucose is oxidized. An energy investment phase of glycolysis uses two atp. An energy payoff phase produces four atp by substrate-level phosphorylation. 1 glucose -> 2 nadh, 2 atp, 2 pyruvate. **where it take place, how much atp is produced, distinguish different types. Inhibition of an enzyme in a pathway by the product of that pathway. High levels of atp inhibit the enzyme phosphofructokinase. The product of this enzyme can be used only in glycolysis. Pyruvate from glycolysis transported from cytoplasm to mitochondria. Positive and negative feedback control on pyruvate dehydrogenase. Large supplies of products (nadh and acetyl-coa) inhibit the enzyme complex.

Related Questions

Which of the following accurately describe difference(s) between oxidative phosphorylation and substrate-level phosphorylation during aerobic respiration in eukaryotes?

	a.	Oxidative phosphorylation relies on energy initially derived from redox reactions to power ATP synthase, and substrate-level phosphorylation relies on enzymatic reactions to phosphorylate ADP.
	b.	Oxidative phosphorylation takes place in the inner mitochondrial membrane and substrate-level phosphorylation only occurs in the cytosol.
	c.	Oxidative phosphorylation uses oxygen as a substrate and substrate-level phosphorylation uses phosphate.
	d.	Oxidative phosphorylation takes place during glycolysis and the electron transport chain and substrate-level phosphorylation occurs during the citric acid cycle and chemiosmosis.
	e.	Oxidative phosphorylation produces less ATP than substrate-level phosphorylation.

QUESTION 1

Which of the following is the correct order of the three stages of cellular respiration?

	a.	Krebs cycle, glycolysis, electron transport
	b.	electron transport, glycolysis, Krebs cycle
	c.	Krebs cycle, electron transport, glycolysis
	d.	glycolysis, Krebs cycle, electron transport
	e.	electron transport, Krebs cycle, glycolysis

1 points

QUESTION 2

Consider a bacterial cell that performs anaerobic respiration. If that bacterial cell had access to six molecules of glucose to use, how many ATP molecules would it be able to produce?

	a.	2
	b.	34
	c.	36
	d.	6
	e.	12

1 points

QUESTION 3

The oxygen that organisms need to live is used exclusively in which of the following metabolic pathways?

	a.	Electron transport chain
	b.	Anaerobic respiration
	c.	Glycolysis
	d.	Krebs cycle
	e.	ATP-Synthase

1 points

QUESTION 4

The electron transport chain uses the energy in NADH and FADH₂ to pump H⁺ ions from the matrix to the innermembrane space. The H⁺ gradient is then used to power ATP-Synthase. Enough H⁺ is pumped from the energy in a molecule of NADH to produce ______ ATP molecules, while enough H⁺ is pumped from the energy in a FADH₂ molecule to produce ______ ATP molecules.

	a.	three; two
	b.	three; three
	c.	two; two
	d.	two; three

1 points

QUESTION 5

Which of the following list contains only products of cellular respiration?

	a.	glucose, oxygen, ADP
	b.	ATP, carbon dioxide
	c.	oxygen, ADP, carbon dioxide
	d.	ATP, glucose, oxygen
	e.	glucose, ATP

1 points

QUESTION 6

What powers the enzyme ATP-Synthase?

	a.	NADH molecules
	b.	oxygen (O₂)
	c.	ATP
	d.	NADH and FADH₂ molecules
	e.	The H⁺ gradient between the matrix and inner-membrane space

1 points

QUESTION 7

Organisms exist which are able to survive using only glycolysis (i.e. without using oxidative phosphorylation).

True

False

1 points

QUESTION 8

Each ADP molecule contains ________ phosphates, and each ATP molecule contains ________ phosphates.

	a.	three; three
	b.	two; two
	c.	one; two
	d.	two; three
	e.	one; three

1 points

QUESTION 9

Adding a phosphate group to ADP to form ATP is an endergonic reaction.

True

False

1 points

QUESTION 10

The majority of ATP produced during cellular respiration is produced during glycolysis.

True

False

1 points

QUESTION 11

Glycolysis occurs:

	a.	on enzymes located in the inner-membrane.
	b.	in the cytosol.
	c.	in the inner-membrane space.
	d.	in the nucleus of the cell.
	e.	in the matrix of mitochondria.

1 points

QUESTION 12

Muscle soreness associated with strenuous exercise is due to:

	a.	the production of alcohol during anaerobic respiration.
	b.	a buildup of lactic acid.
	c.	an excessive amount of ATP that builds up during exercise.
	d.	the large amounts of CO₂ building up in the muscle.

1 points

QUESTION 13

A required reactant for glycolysis is:

	a.	the electron transport chain.
	b.	carbon dioxide.
	c.	oxygen.
	d.	NAD+.
	e.	mitochondria.

1 points

QUESTION 14

NADH is produced in all of the following except:

	a.	the electron transport chain.
	b.	the Krebs cycle.
	c.	glycolysis.

Question 1 Organisms exist which are able to survive using only glycolysis (i.e. without using oxidative phosphorylation).
True
False

Question 2 Glycolysis occurs:
a. in the matrix of mitochondria.
b. in the inner-membrane space.
c. in the cytosol.
d. in the nucleus of the cell.
e. on enzymes located in the inner-membrane.

Question 3 Muscle soreness associated with strenuous exercise is due to:
a. the large amounts of CO2 building up in the muscle.
b. an excessive amount of ATP that builds up during exercise.
c. a buildup of lactic acid.
d. the production of alcohol during anaerobic respiration.

Question 4 Each ADP molecule contains ________ phosphates, and each ATP molecule contains ________ phosphates.
a. two; three
b. two; two
c. three; three
d. one; three
e. one; two

Question 5 The oxygen that organisms need to live is used exclusively in which of the following metabolic pathways?
a. Glycolysis
b. Electron transport chain
c. Krebs cycle
d. Anaerobic respiration
e. ATP-Synthase

Question 6 NADH is produced in all of the following except:
a. the electron transport chain.
b. glycolysis.
c. the Krebs cycle.

Question 7 Consider a bacterial cell that performs anaerobic respiration. If that bacterial cell had access to six molecules of glucose to use, how many ATP molecules would it be able to produce?
a. 36
b. 6
c. 12
d. 34
e. 2

Question 8 The majority of ATP produced during cellular respiration is produced during glycolysis.
True
False

Question 9 What powers the enzyme ATP-Synthase?
a. The H+ gradient between the matrix and inner-membrane space
b. ATP
c. oxygen (O2)
d. NADH molecules
e. NADH and FADH2 molecules

Question 10 Which of the following list contains only products of cellular respiration?
a. ATP, glucose, oxygen
b. ATP, carbon dioxide
c. oxygen, ADP, carbon dioxide
d. glucose, ATP
e. glucose, oxygen, ADP

Question 11 Adding a phosphate group to ADP to form ATP is an endergonic reaction. True False

Question 12 The electron transport chain uses the energy in NADH and FADH2 to pump H+ ions from the matrix to the innermembrane space. The H+ gradient is then used to power ATP-Synthase. Enough H+ is pumped from the energy in a molecule of NADH to produce ______ ATP molecules, while enough H+ is pumped from the energy in a FADH2 molecule to produce ______ ATP molecules.
a. two; three
b. three; three
c. three; two
d. two; two

Question 13 Which of the following is the correct order of the three stages of cellular respiration?
a. glycolysis, Krebs cycle, electron transport
b. Krebs cycle, electron transport, glycolysis
c. electron transport, Krebs cycle, glycolysis
d. electron transport, glycolysis, Krebs cycle
e. Krebs cycle, glycolysis, electron transport

Question 14 A required reactant for glycolysis is:
a. carbon dioxide.
b. mitochondria.
c. NAD+.
d. the electron transport chain.
e. oxygen.

maroonguinea-pig450

BIO203H5 Lecture Notes - Lecture 11: Pyruvate Dehydrogenase, Acetyl-Coa, Oxidative Phosphorylation

Document Summary

Get access

Related textbook solutions

Molecular Cell Biology

Biology: Science for Life with Physiology

Concepts of Biology

Biology

Essentials of Biology

Related Documents

BIO203H5 Lecture Notes - Lecture 12: Electron Acceptor, Citric Acid Cycle, Pyruvic Acid

BIO203H5 Chapter Notes - Chapter 9: Oxaloacetic Acid, Atp Synthase, Cell Membrane

BIO203H5 Lecture Notes - Lecture 9: Endergonic Reaction, Oxidative Phosphorylation, Exergonic Reaction

Related Questions