BIOC65H3 : BIOC65 - review.docx
12 Dec 2013
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Systemic: when it effects somewhere that it didn"t originally start of effecting. Slide 31: number of animals effect it because of its statistical significance, larger number, more significance, and it decreases your error bars. If you only have two animals in your test you will have bigger error bars, and more animals help you detect statistical difference and decrease your error bars: range between the noael and loael: Slide 44: potency: at a lower concentration you have a bigger effect. Not as important for drugs because you just prescribe a bigger dose. Frequency of elimination slide (60): single dose: Compound a: if you get exposed once, the amount does not get eliminated. Compound c: gets reduced the fast: repeated dose: Compound a: when you get more and more, the concentration will constantly be increasing. For compounds that don"t get eliminated, concentrations will continually go up.
