NFS284H1 Lecture Notes - Angiotensin, Bone Resorption, Absorption Edge
Document Summary
Sodium: high proportion of sodium intake above the ul, regulation of blood pressure. Bp renin released from kidney angiotensin converted into angiotensin ii. Angiotensin ii constricts blood vessels bp. Angiotensin ii aldosterone released from adrenal gland sodium reabsorbed into the kidneys water retention bp: hypertension. Sodium intake blood sodium levels bp. Most individuals: bp sodium excreted from the kidneys water excretion bp. Salt-sensitive individuals: bp sodium excretion constriction of blood vessels bp, no additional benefit of lowering sodium intake from ul = 2300 mg to ai = 1500 mg. May be potentially harmful for certain groups. Average sodium intake is above the ul = 2300 mg. Potassium: potassium intake may or may not be adequate. <50% of the population has an intake greater than the ai: high [k+] inside the cell. High blood pressure: gestational hypertension, pre-eclampsia (e. g. , high bp, fluid retention, rapid weight gain, eclampsia (e. g. , seizures, death) Not related to diet but calcium supplements may be beneficial.
