HLTH340 Study Guide - Distal Convoluted Tubule, Proximal Tubule, Chemical Weapon

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Expound as necessary: excretion: removal of an endobiotic or xenobiotic out of the body in waste matter. Urine is a liquid material manufactured by the kidneys. Feces -- waste matter from digested food but also the liver contributes to it (recall how bile is created in the liver and secreted into the intestine where all the food is) May or may nor require energy (some passive, some active: secretion: transport of an endobiotic or xenobiotic out of body by a non-waste fluid. Often secondary route of xenobiotic elimination (e. g. breast milk, semen) - more later: elimination: removal of a xenobiotic from the bloodstream by a combination of biotransformation (metabolism) and excretion, clearance: removal of a xenobiotic from bloodstream by a combination of tissue sequestration (distribution), biotransformation (metabolism) and excretion. It is more general to be aware of the difference. Discuss the major excretion pathways: kidney: urinary excretion (mainly hydrophiles) liver: biliary excretion (mainly lipophiles)