ANTB15H3 Study Guide - Infant Mortality, Birth Weight, Zygosity
Document Summary
Hemoglobin polymorphism: endemic, fatal: pre, during, and post, there should be gene for resistance. Factors: plasmodium mosquitoes human plasmodium mosquitos - human. Children are most susceptible: responsible for 1-3m deaths/year, 25% infant deaths in africa, 30 mosquito species, 80% infection rate of red blood cells, cause other forms of malaria. Bites an individual with malaria, then bites individual with no malaria. The cycle is typically between people and mosquitoes (although can also be with apes and. 90% humans: parasites reproduce in the liver, cycles the body, produces gametocytes, sucked up, oocytes develop in mosquitoes tummy, into sporozoites, transmits to human body by biting (saliva). Carry oxygen from the lungs (via arteries and capillaries). Carry co2 back to the lungs, release o2 and co2 is dumped. The rest of the body is low o2 pressure; Point mutation codes for protein chain of hb. Error synthesis at the 6th position on the beta chains.
