BIOL 133 Chapter Notes - Chapter 1: Gregor Mendel, Hemoglobin, Menopause

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20 Jan 2014
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Important terms: genes and alleles, dna and rna, chromosomes, genome, genotype. Gene segment of dna (a gene codes for production of a protein) Example: sickle-cell anemia: caused by mutated gene - codes for component of hemoglobin, an allele of the gene codes for a defective hemoglobin, result is sickle-cell anemia. Dna and rna: dna = deoxyribonucleic acid. 4 dna building blocks: a, t, g, c. 4 rna building blocks: a, u, g, c. Chromosomes: long strand of dna and proteins. Each chromosome contains many genes: humans: 46 chromosomes in all cells except sperm and eggs. Genomes: all genes in cells of a particular type of organism, human genome is approximately 20,000 genes, corn has 30,000 genes and the worm c. elegans has 10,000. Phenotype how those alleles are expressed (what the organism looks like). Mendelian traits: one gene causes a specific phenotype (disease, examples: sickle-cell anemia, cystic fibrosis, hemophilia. One gene does not lead to one disease.

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