BIOL 133 Study Guide - Final Guide: Signal Transduction, Globin, Anorexia Nervosa
Document Summary
Genetic determinism: the idea that our genes solely determine who we are. *two factors responsible for variation in organisms genes and environment* About 180 genes determine height: quantitative trait loci (qtls): the bell shape distribution traits cardiovascular disease, height, skin color, it is difficult to predict recurrence for polygenic traits. Heritability: % of phenotypic variation due to genes --- h, h=1 genes only, h=0 environment only, correlation coefficient proportion of genes relatives share. Heritability: proportion of people sharing a trait compared to proportion predicted to share trait. Mendelian trait: expect it in 50 sibling pairs. If trait is only observed in 37 pairs, the heritability = . 37/. 50 = . 74 or 74% Observed/expected: heritability is component of phenotype attributed to genes, in lab animals and plants heritability is easy to determine, humans are not so easy. Adoption studies: adopted people share environment but not genes with adoptive family, share genes but not environment with biological parents.
