PSY 214 Chapter Notes - Chapter 1: Bioavailability, Hydrolysis, Cytochrome P450
23 Jan 2014
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Document Summary
Pharmacology: the scientific study of the actions of drugs and their effects on a living organism. Neuropharmacology: concerned with drug-induced changes in the functioning of cells in the nervous system. Psychopharmacology: emphasizes drug-induced changes in mood, thinking and behaviour. Neuropsychopharmacology: identifies chemical substances that act on the nervous system to alter behaviour that is disturbed from injury, disease or environment. Drug action: molecular changes produced by a drug when it binds to a particular target. Placebo effects and double blind experiments: double blind experiment: neither the patient nor the observer knows what treatment the patient has received. While in the blood, a drug may also bind (depot binding) to plasma proteins or may be stored temporarily in bone or fat, where it is inactive. Inactivation: aka biotransformation, occurs as a result of metabolic processes in the liver. The amount of drug in the body at any time depends on the balance b/w absorption and inactivation.
