CSB328H1 Study Guide - Final Guide: Aureus, Sos Response, Operon
25 Jan 2014
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Lecture 26: virulent (lytic) phages (dsdna virus w tail) have one objective get in, replicate, kill host, 43 life cycle/ life style get out: are bacterial killing machines, other two life cycle stages don"t involve killing the host. 1. filamentous phage (release ssdna) don"t have tails. 1. they replicate as a plasmid w/in a cell but they secrete the plasmid coated in protein w/o killing the cell itself. 44: phages recognize cell surface receptors on bacterial prey (recognize lps o-antigen, after tail makes contact, will go into firm attachment phase and docks w porin protein. 7. tail recognizes that attachment has occurred, goes through tail contractions and becomes a dna-injection syringe. 9: make proteins that make the body of the phage themselves, assembly of phage particles w/in the cell, lysis, phage dictates when lysis occurs and will oonly occur under sufficient number and maturity, lysozyme enzyme will degrade pg.
