HMB265H1 Lecture 9: Lecture 9 Readings

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25 Oct 2011
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HMB265H1 Full Course Notes
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HMB265H1 Full Course Notes
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The frequency of recombinants produced by crossing over is they key to chromosome mapping. Recombinant frequencies less than 50 percent are different linked (unlinked) genes. The farther apart the genes are, the more closely their recombinant frequencies approach 50 percent. Linkage map: a chromosome map; an abstract map of chromosomal loci that is based on recombinant frequencies. The greater distance between the linked genes, the greater then chance of crossovers in the region between the genes, and the greater the proportion f recombinants would be produced. Determining frequency of recombinants, we can measure map distance between genes. ): a distance on the chromosome map corresponding to 1 percent recombinant frequency. cells or individuals. Recombinant frequency (rf): the proportion (or percentage) of recombinant. Crossovers produce recombinant chromatids whose frequency can be used to map genes on a chromosome. Recombination between inked genes can be used to map their distance apart on a chromosome.

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