HK 2810 Lecture Notes - Aromatase, Vascular Smooth Muscle, Adrenocorticotropic Hormone

• School: University of Guelph
• Department: Human Kinetics
• Course: HK 2810
• Professor: Coral Murrant

Document Summary

Stored in secretory vesicles prior to release. Requires plasma membrane receptor on target tissue: metabolites of amino acids (amines) Epi and ne, dopamine, serotinin, thyroid hormone (ls) Nls stored in secretory vesicles prior to release. Nls - require plasma membrane receptor on target tissue. Ls - cytosolic or nuclear receptor on target tissue: metabolites of cholesterol - steriod hormones. Cytosolic or nuclear receptors: communication - hormones. General characteristics: 1/2 life in blood, carrier proteins, hormones circulate bound to a carrier or free. Only free hormone is available to interact with target: provides reservoir, extends 1/2 life, target tissue receptors required. Hormone a must be present to get full effect of hormone b: communication - hormones. Hypothalamus hormone 1 secretion hormone 1 in blood. Anterior pituitary hormone 2 secretion hormone 2 in blood. Endocrine gland hormone 3 secretion hormone 3 in blood target cells change cell function: communication - hormones. 3: cyclic secretion - oscillating, pulsatile cycles following circadian rhythms.