Biochemistry 2280A Lecture Notes - Asymmetric Cell Division, Chelation, Cell Culture
4 Feb 2014
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What is cell biology: cell biology is an academic discipline that studies cells, the basic structural, functional and biological unit of all known. Lecture 1: introduction to cell biology organisms: cell biologists look at all aspects of the cell, cell structure, cell organelles and membrane trafficking, cell cycle, division and death, cell movement, cell signaling, cell communication. Storehouse for thousands of genes: determine what is normal so we can fix the abnormal . Lead to nobel prize: ultimate goal: to understand how macromolecular systems and organelles work and cooperate to enable cells to function autonomously and in tissues. How do we study cells: hypothesis-driven experiments. Primary cell culture refers to cells taken directly from an organism. These cells usually divide a limited number of times (~50 generations, hayflick limit). Stem cells can divide symmetrically, giving rise to two stems cells, and these divide to produce two stem cells each, and so on, producing more.
