PSYB30H3 Study Guide - Final Guide: Globules Of Fat, Physostigmine, Pathogenic Bacteria
Document Summary
Psychopharmacology study of how drugs affect the nervous system and behavior. A substance that acts to alter mood, thought, or behavior. Route of administration:the way the drug enters the body and reaches its target. Oral: natural and generally the safest, has to go through many obstacles in the digestive system. Inhalation: few barriers: drugs can be injected into the: bloodstream, muscles, brain & absorption through the skin. Drugs are metabolized in the kidneys, liver, and bile. Drugs are excreted in the urine, feces, sweat, breast milk, and exhaled air. Brain capillaries composed of endothelial cells that have tight junctions. Endothelial cells are surrounded by the end feet of astrocytes, help exchange food and waste and maintain tight junctions. Small molecules and fat soluble molecules can pass through. Several areas of the brain lack the tight junctions. Pituitary gland: allows entry of chemicals that influence hormone secretion. Area postrema: allows entry of toxic substances to trigger vomiting.
