PSY 434 Lecture Notes - Acetyl Group, Carboxylic Acid, Muscarine
10 Feb 2014
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Choline from dietary fat acetyl coenzyme a (acetyl coa) from fats and sugars. 5-http: gives more immediate precursor for serotonin: we eat tryptophan to boost our serotonin levels, it gets converted to 5-ht, to increase brain tryptophan need to ingest in absence of other proteins and high (serotonin) carbs. Drugs that affect ach storage and release: ach is stored in vesicles. Must be administered ahead of time: during first gulf war soldiers were instructed to take 3 tablets daily when at risk for nerve gas, animal studies had shown low risk for crossing blood brain barrier (bbb), unfortunately it appears that stress can increase the level at which this drug crosses the bbb. Saporin is a neurotoxin: when injected into the ventricular system the bfcs neurons take in this substance, those neurons are selectively destroyed, affects learning and memory i. e. , berger sweeney et al. (1994)
