PSL300H1 Lecture Notes - Lecture 5: Posterior Pituitary, Descending Limb Of Loop Of Henle, Proximal Tubule
Document Summary
Water distribution in body: ~55% water, 2/3 intracellular fluid, ecf 1/3, water balance o. Intake (food, drink @2. 2 l/day) + metabolic production (. 3 l/day) = output [ urine o. @ 1. 5 l/day, sweat, breath @ . 9l/day, feces @ . 1 l/day: 2. 5 l out = 2. 5 l in. Osmolarity difference between surface and medulla: nephron is the functional unit of the kidney, urine is formed in the nephron by filtration, reabsorption, secretion. Isosmotic fluid leaving the proximal tubule becomes progressively more. Inner part of medulla (where loop of henle is located, 1200 mosm, from 300. 1. concentrated in the descending limb, only water absorbed. Vasopressin (antidiuretic hormone , adh: synthesized in the hypothalamus (contained in vesicles, secreted from the posterior pituitary, sometimes called arginine vasopressin. Aldosterone synthesis controlled by negative feedback: simple (k+, osmolarity, complex (renin-angiotensin ii, stimulators, high [k+] in plasma, angiotensin ii, inhibitor, high osmolarity (ecf, renal juxtaglomerular cells secrete "renin", an enzyme involved in controlling aldosterone release o.
