PSL300H1 Lecture Notes - Sexual Differentiation, Epididymis, Seminal Vesicle

54 views2 pages
School
Department
Course

Document Summary

Somatic cells contain 46 chromosomes: meiosis reduces number to 23 chromosomes, female ovary, male testis. At 6 weeks the fetus has bipotential primordium and rudimentary male and female reproductive tracts: mullerian duct -> fallopian tube, uterus, upper vagina, wolffian duct -> epididymis, vas deferens, seminal vesicle. Y chromosome has sry gene that promotes testes development: altered y chromosome lacks sry gene, codes for a gene regulatory protein (transcription factor. Secrete testosterone (controls development of wolffian duct into. Testosterone converted to dht with 5a reductase which controls the. Sry gene protein in a male embryo directs the medulla of the bipotential gonad. Anti mullerian hormone from testis causes the mullerian ducts to degenerate. Testosterone from testis converts wolffian duct into seminal vesicle, vas deferens. Testes descend from the abdominal cavity into the scrotum. Females: have rspo -> wnt4 beta catenin (grp that suppresses sox9 expression, no amh or testosterone. Gonadal cortex becomes ovary in the absence of sry protein.

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents