PSL300H1 Lecture Notes - Prostaglandin, Anterior Pituitary, Progenitor Cell
Document Summary
Where does fertilization occur: oocyte viable for 24h ,sperm for 4-6 h, sperm deposited in vagina must mature and travel before fertilization, sperm undergoes capacitation, becomes hyperactive, albumin ,enzymes, lipoproteins bind to sperm: Develop strong whip like motion: sperm must pass through (~30 min) cervical mucous (thin, estrogen -> gets thinner with estrogen, thicker with progesterone, uterine and oviduct contractions aid transport. Days 2-4 cell division takes place in fallopian tube (fallopian tube relaxed. 3: blastocyst consists of trophoblast and inner cells (embryo and other structures) Days 5-9 blastocyst implants (invades the uterine endometrium) Implantation: decidua produced from endometrial cells, secrete several hormones and growth factors, surface of uterine lining closes in after the blastocyst has been implanted. Placental circulation: maternal endometrial vessels will break down, the mother"s blood and the fetal blood does not usually mix, easy gas exchange between the maternal blood vessels and the umbilical vein.
