BIOL299 Lecture Notes - Lecture 15: Sickle-Cell Disease, Zygosity, Population Genetics

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Population genetics cont"d: does recessive mean rare? (e. g. wrong answers to midterm question c2) No !! e. g. rare, dominant (ad, xd) diseases in humans . No !! e. g. rare, dominant (ad, xd) diseases in humans e. g. o blood type is most common and is homozygous recessive. True: (1) mutations are rare (2) most mutations are recessive . But this does not mean that mutations are recessive because they are rare (or vice versa): hardy weinberg equilibrium (review) Yes !!! e. g. there can be random mating in a large population with no migration, but selection could affect the frequency of alleles at one locus, but not another. 99 real cats described in survey; raw data is on e-class. 21 pure white (w_) not pure white (ww) short (l_) long (ll) 0% to 50% white (ss) 1 39. 0. 15 99 cats = expected if hwe.

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