BIOL 200 Lecture Notes - Lecture 14: Contig, Dna Annotation, Arabidopsis Thaliana
Document Summary
In this lecture, new methods of dna sequencing, which replace the original dideoxy. Sequencing method (sanger sequencing) the way the human genome has been originally sequenced are presented. Determining the dna sequence of the genome: to identify the location of genes (process of genome annotation). Popular theme: looking at -omics in a more holistic way. 1: plant (arabidopsis thaliana): common weed often found in the cracks of sidewalks and other places this fast growing plant is easy to sequence, because it has a small genome that is easy to manipulate. Model organism despite its lack of agricultural benefit: now: there are over 2000 complete/ongoing eukaryotic genome projects [sequencing projects, chimpanzee, fugu fish: model system for invertebrates. Easy to sequence, because it has a very streamline genome with very few transposable elements to get in the way of understanding what the genes do: sea squirt: model for vertebrae development (similar to the zebrafish).