PSYC 3403 Lecture Notes - Lecture 10: Food Addiction, Neuropeptide Y, Anorectic

• School: Carleton University
• Department: Psychology
• Course: PSYC 3403
• Professor: Tarry Ahuja

Document Summary

Factors that mediate food intake: homeostasis (energy demands) (body"s basic needs, emotional state (stress, boredom, hedonism (pleasure) Body has humoral signals from body to hypothalamus that you are hungry, and initiate cascade of events to make you seek food. Many triggers, such as seeing friends eating and drinking. Hunger-stimulating gi peptides: ghrelin (stomach, pancreas) Activates a portion of the dopamine reward pathway. Mechanism of action for leptin at hypothalamus: antagonizing the effects of neuropeptide y (stimulant, antagonizing the effects of anandamide, promote synthesis of -msh (appetite suppressant) Hypothalamus- primary regulatory center for food intake and body weight: mice were very obese, helped in the discovery of leptin, administration of leptin reversed the effect. The hypothalamus has two distinct regions: ventromedial hypothalamus (deals with satiety, aka off switch, lateral hypothalamus (deals with hunger, aka on switch) Each region regulates the opposing action: hunger vs. satiety.