CHY 204 Chapter Notes - Chapter 11: Lipid Bilayer, Fluid Mosaic Model, Lipid Bilayer Fusion

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Membranes define the external boundaries of cells & regulate the molec traffic across that boundary. In eukaryotic cells, memnranes divide the internal space into discrete compartments to segregate processes & components; they organize complex rxn seq that are central to biological energy conservation & cell-cell comm. There are cell membranes, organelle membranes w/ thin lipid bilayers. Biological membranes have a trilaminar appearance, 5-8a thick; 1 nm=10^-9 m & 1 a =10^-10. Fluid mosaic model of membranes: the fatty acyl chains in the interior of the membrane form a fluid, hydrophobic region. Integral pro float in the sea of lipids held by hydrophobic interactions w/ their nonpolar aa side chains. Both pro & lipids are free to move laterally in the plane of the bilayer b/c are mostly held by noncovalent interactions but movement of either from one leaflet of bilayer to another is restricted.

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