HES 319 Lecture Notes - Chemotherapy, Sensory Cortex, Neural Coding
Document Summary
Rapidly adapting receptor: turns on and off fast, on for less time. Slowly adapting: turn on and off slowly, on longer. Meissner"s corpuscles fine, light touch, rapidly adapting, numerous. Merkel disk receptors pressure, slowly adapting, numerous. Pacinian corpuscles vibration, pressure, rapidly adapting, less numerous (deep pressure) Ruffini ending skin stretch, slowly adapting, less numerous, lined up so they can convey stretch direction. Glabrous skin hairless (palm verses back of hand, top vs bottom of foot) Neuropathy can occur due to diabetes or chemotherapy. Action potentials are the individual elements of the code the cns receives. Frequency of action potentials is dependent on stimulus strength. Frequency of action potentials correlates with the perceived sensation. Neural coding of stimulus intensity or faithfully transmitted to the sensory cortex. Adaptation of receptor firing occurs after stimulus onset. Rapidly adapting receptors inform cns about changes in stimulus intensity.
