PSL301H1 Chapter Notes -Connective Tissue, Apoptosis, Complement System
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PSL301H1 Full Course Notes
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Pathogens and innate immunity (802-814: main features of immune system are specificity and memory, allow body to distinguish between self from non-self during immune response, 3 major functions. Recognize and remove abnormal self cells: cancer cells form regularly but are usually detected and destroyed by immune system before they get out of control. Remove old, dead or damaged cells: scavengers cells such as macrophages patrol extracellular compartments. Free of capsid shell, virus rna/dna hijacks the cell"s transcription and translation machinery to make new viral nucleic acid and proteins. Can be released in 2 ways: virus causes host to lyse and release viral particles into ecf, virus particles embed themselves into a vesicle then bud off. Immune response is divided into 2 categories: innate immunity is present from birth and is the nonspecific immune response. Membrane receptors have broad specificity, allowing them to respond to molecular signals to various pathogenic microorganism.