Anatomy and Cell Biology 3309 Lecture Notes - Basal Lamina, Tyrosinase, Keratin

• School: Western University
• Department: Anatomy and Cell Biology
• Course: Anatomy and Cell Biology 3309
• Professor: Ron Podesta

Document Summary

Hypodermis: loose ct . mainly adipose tissue. (called superficial fascia in gross anatomy). Derivatives of skin include sweat glands, hair, sebaceous glands and nails. Function: protection, prevent water loss, pns receptors, vitamin d production, heat regulation, waste product secretion, immunologic functions langerhans cells antigen processing. Thin skin has hair. thick and thin refer to epidermis only. Thick skin has a thinner dermis than thin skin. Thick skin found on palms and soles of feet. Thick skin: 5 layers: stratum basale=stratum germinativum, progenitor cells constantly renew epithelium, stratum spinosum, nodes of bizzozzaro = desmosomes, stratum granulosum, keratohyalin granules, stratum lucidum, eosinophilic refractile cells containing large amounts of keratin nuclei not visible. Only in thick skin: stratum corneum, no cytoplasmic organelles, cell membranes coated with glycolipid (acylglucosylceramide, gets thicker when exposed to more wear and tear: callus formation. Dermal papillae epidermal ridges interpapillary pegs: down growth of epidermis into dermis where sweat duct passes from dermis to epidermis.