Biology 1001A Lecture Notes - Lecture 15: Chromatin, Methylation, Cytosine

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Reasons why, if identical twin women have sons with identical twin men, the sons will not be identical - The gametes of the two couples will be different as sexual recombination occurs and will result in variation. Definition or explanation of heritability with respect to human disease risk - Heritability of a trait is the observable differences between individuals due to genetic differences. Characteristics that would, and would not, be different between monozygotic (identical) twins. Random x inactivation in females; inactivated different x"s in different tissues. Their gametes are different due to sexual recombination. Process of random x inactivation leading to genetic mosaicism - Fertilized zygote divides and at about 100 cells stage, each cell will inactivate one of it"s. X chromosomes, either the maternal or paternal x. This process of either x being inactive will occur at random with different cells having different x chromosomes being inactive.

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