Biochemistry 2280A Chapter Notes -Oxidative Stress, Growth Factor, Progenitor Cell

• School: Western University
• Department: Biochemistry
• Course: Biochemistry 2280A
• Professor: Christopher Brandl

Document Summary

Cancer is a disease characterized by the rapid proliferation of an abnormal cell derived. Cancers can be benign (they do not spread) or malignant (the cells have the ability to from one of the organism"s own cells invade surrounding tissues) In this regard, cancer is a genetic disease, a point highlighted by fact that many cancer causing agents damage dna. These cancer causing agents include: radiation and chemical mutagens. In many cases, pinpointing the origins and pathways resulting in disease is not simple; this is because a single mutation is not sufficient to cause disease. The need to accumulate multiple mutations is one of the reasons why cancer is more prevalent in older individuals. A slow accumulation of specific mutations can eventually result in disease. Tumour progression involves successive rounds of mutation and selection for specific properties that will enhance or otherwise alter cell growth.