PSYC62H3 Chapter Notes - Chapter 4: Radioligand, Neurotransmitter Receptor, Comt Inhibitor
Document Summary
Pharmacokinetics: how drugs move throughout the body. This process involves factors concerning how a drug is administered and how it is absorbed into the bloodstream, permeates different body parts, and is eliminated from the body. Many therapeutic drugs fail in clinical testing because they are inadequate in reaching the areas of the body necessary for the drug"s actions, making the treatment useless. Pharmacodyamics: how drugs cause biological changes in the body. Pharmacokinetic properties and drug passage through the body: Absorption: entry of a drug into the circulatory system (to do so, a drug must pass through different membranes such as the mucus membranes in the mouth or the walls of the intestines: fig 4. 1 & table 4. 1) Most therapeutic drugs are orally administered because it is easier than giving ourselves an injection. Therefore, developers must find ways to protect the drug from digestive acids in the stomach. Encasing a drug within a tablet or capsule will manage this.
