PSYC 3403 Lecture Notes - Monoamine Oxidase, Alpha Helix, Basketligan

• School: Carleton University
• Department: Psychology
• Course: PSYC 3403
• Professor: Tarry Ahuja

Document Summary

Overview: receptor as a site of drug action, dose-response curves, drug safety, effectiveness. Pharmacodynamics is the study of the biochemical and physiological effects of drugs and the mechanisms of drug action and the relationship between drug concentration and effect. L refers to anything that interacts with a neurotransmitor (ligan) R (receptor) r is the keyhole in the process (accepting) Double sided arrow because it is in constant flux. Receptors (characteristics: membrane-spanning protein, binding sites for endogenous nts and drug molecules (drugs are exdrogenous) Receptors (characteristics: composed of 7 or 12 alpha helical coils, nt"s and drugs binds within tm coils held by ionic forces. Receptors (characteristics: reversible binding activates receptor causing conformational change, intensity of signal determined by number of percentage of drug-receptor interaction, nt"s and drugs interact with binding site on receptor or to a nearby site. Receptors (binding: initiate cellular response similar or identical to that of nt (agonist)