NATS 1670 Lecture Notes - Rabies Vaccine, Attenuated Vaccine, Louis Pasteur

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Vaccines are harmless agents, perceives as enemies. Trigger active immunity, stimulating the body to defend itself: provide protective immunity against a potential pathogen. 2000bc: sniffing of smallpox crust in china. Variolation: inoculation with the wild type smallpox. The difference between variolation and vaccination is that vaccination is an agent; variolation is a virus that causes the disease. 1796: edward jenner discovers a safe smallpox vaccine. This vaccine has been used for over 200 years. When we were able to eradicate small pox from the world, we were able to use the same thing. This disease killed 300 million people every 100 hundred years. This was a huge success in terms of stopping this disease. Louis pasteur: in 1885 louis pasteur developed the first attenuated vaccine against rabies virus, attenuation was achieved by creating a virus strain that were less virulent for humans.

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