KINE 2011 Lecture Notes - Hyperaemia, Sympathetic Nervous System, Blood Vessel

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Local control of blood flow: active or reactive hyperemia. Active or reactive hyperaemia= relationship between disturbance in metabolites that will cause vasodilation of arterioles. 2 diff ways to disturbance of metabolites (i)enhancing metabolic activity of cells surrounding blood vessels (ii)accumulation because we have reduced flow to the area. As the adenosine diffuses and reaches the smooth muscle causes and starts smooth muscle cells it to relax, we see a much larger increase in diameter of blood vessels and now u can see rich network of blood flow. Norepinephrine is added which causes vasoconstriction and prevents blood from moving downstream capillaries. Once its removed, it comes to its resting diameter again. Vasodilator is added, adenosine is going on to the blood vessel, and the capacity of blood vessel to go in opposite direction and opens up a lot of capillaries. Local control of blood flow is not associated with metabolic demands.

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