BIO-0013 Lecture : 13.1, 13.2 Class Notes.docx

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Interphase: chromosomes replicate in parent cell; uncondensed chromosomes: early prophase i: chromosomes condense; nuclear envelope breaks up; spindle apparatus forms; synapsis (pairing) of homologous chromosomes, homologous chromosomes line up next to each other (instead of along one plane in mitosis) (cid:224) allows for crossing over, tetrad = 4 chromatids from homologous chromosomes, late prophase i: crossing over of non sister chromatids (often multiple crossovers between the same chromatids, crossing over occurs between homologous chromosomes. Synaptonemal complex is destroyed after crossing over: metaphase i: tetrads migrate to the metaphase plate, anaphase i: homologs separate and begin moving to opposite sides of the cell, telophase i and cytokinesis: chromosomes move to opposite sides of the cell, which then divides, prophase ii: spindle apparatus forms, metaphase ii: chromosomes line up at middle of cell (metaphase plate, anaphase ii: sister chromatids separate, begin moving to opposite sides of cell, telophase ii and cytokinesis: chromosomes move to opposite sides of cell, then cell divides.

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