SOCR 330 Lecture Notes - Sex Linkage, Zygosity, Genetic Drift
Document Summary
Study of genetic variation in populations and how it changes over time. Frequency of phenotypes in a population linked to abundance of alleles influencing those traits. Group of interbreeding individuals living in same area and sharing common set of genes. Relative proportions of different genotypes in a population. All alleles shared by individuals in a population. Spatial or temporal patterns of genetic variation within or among populations. Describes mathematically the relationship between allele frequencies in gene pool and genotype frequencies in population. After one generation of random mating genotype frequencies will be p2:pq:q2. Using hardy-weinberg to estimate number of carriers in a population. In 1904 an estimate 1 in 1000 hopi individuals albino so q2 = 0. 001 and q = 0. 032 (frequency of albino allele) Frequency p of normal allele = (1 q) = 0. 968. Frequency of heterozygote carriers: 2pq = 2 (0. 968) (0. 032) = 0. 062 or 6. 2% Allele frequency same in both male and female gametes (no sex linkage)
