BIOL 2020 Lecture Notes - Phagocytosis, Cyclin-Dependent Kinase 1, Thymosin

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Cell bio-feb 20 brownian rachet: process by which the chaperones pull the protein inside the matrix. Chaperones come one by one, slowly pulling it down. mitochondrial processing peptidase cuts off pre-sequence. And then the protein can fold into its native structure. Intermediate filaments: cell specific neurons-- neurofilaments skin cells - keratin. Determine cell shape positions organelles in the cell directs the movement of materials and organelles in cells moves cells from place to place mitosis and cell division. Microtubule-associated proteins (maps) structural maps stabilizing proteins; prevent microtubule from falling apart on its own. Map1, map2, map4, tau clamps onto the side of the microtubule and prevents the subunits from falling away. Microtubule-associated motor proteins kinesin goes in anterograde dynein retrograde. Pcm initiates microtubule formation minus end close to centrosome. Dynamic properties of microtubules assembly and disassembly is temperature dependent. Gtp required for microtubule assembly must be bound to beta-subunit.

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