LMP299Y1 Lecture Notes - Lecture 7: Team Ldlc.Com, Hyperlipidemia, High-Level Data Link Control

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Lecture 7: lipids and cardiac disease the fibrous cap holds the wall together. Ischemic heart disease ischemic heart disease (ihd) is the 2nd most frequent cause of death in canada, just behind cancer. Mortality rate has been declining since 1970, possibly due to better eating habits, more exercise, and better treatment. Ihd kills as many women as men, but few women develop symptoms before age 60 years (later in women) Symptoms in women are less characteristic than those in men, leading to under diagnosis. Schematic time course of human atherogenesis. Fasting (endogenous pathway) still need to get energy to muscles and tissues liver generates vldl very low density lipoprotein. Vldl carries triglycerides to muscle and adipose cells. In this process it gets smaller becomes idl (intermediate density lipoprotein) Idl can go back to the liver or get further processed into a ldl particle (low density lipoprotein) After ldl is processed, it goes back to the liver.

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