HMB200H1 Lecture Notes - Tetrodotoxin, Visual Cortex, Apoptosis
Document Summary
Lecture 21: brain growth and neural connections. Proteins expressed in specific neurons. Cell survival is stimulated by neurotropic factors. Can extract growth factors from brain bndf (brain derived neurotropic factors) Can extract growth factors from glia glial factor. Chemical induction factor that allows them to survive or not. Competition involves chemical signals (e. g. , trophic signals) and electrical signals (activity- dependent plasticity): more inputs more dendrites more synapses. Brain systems for studying connections. Crossing fibres of ventral spinal cord. (netrin attracts, slit repels axons) If you take a retina, and put it near the colliculus, those retinal axons will grow out towards the. In experimental embryology: single chemicals can change the growth, single genes can change the growth influences connections and behaviour. Synaptic connections formed at different times in different brain areas. Later on, these are influenced by neural firings: neural firings occur later in development (especially in the cortex after birth)
