MICRB265 Lecture Notes - Lac Repressor, Lac Operon, Antisense Rna
10 Apr 2014
School
Department
Course
Professor
Document Summary
This chapter introduces the principles of metabolic regulation to demonstrate how the various pathways and activities of microorganisms discussed in previous chapters are coordinated. The chapter begins with a discussion of the need for regulation and then describes different mechanisms by which prokaryotes regulate metabolic activities. Allosteric regulation is the fastest because it is at the enzyme, or posttranscriptional, level. Examples of positive and negative regulation of transcription is discussed in detail. The final part of the chapter discusses global regulatory networks where single molecules control expression of multiple genes, using quorum sensing systems as the primary example. Chapter outline: prokaryotic gene expression, organization of genes on dna strands: A gene is a dna segment or sequence that codes for a polypeptide, rrna, or trna. In prokaryotes, genes are not usually interrupted by introns as they are in eukaryotes. However, multiple genes can be coded on a single polycistronic mrna.
