Health Sciences 2711A/B Study Guide - Neuropathology

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Document Summary

March 5, 2014: longitudinal study of aging and alzheimer disease in 678 catholic sisters who are members of the school sisters of notre dame congregation; participants 75 102 years old at the beginning in 1991, and the oldest member had survived to 107 years by 2002, three basic sources of data available about participants, convent archives provide info about potential early and middle life risk factors for alzheimer disease and other disorders, annual examinations document changes in the cognitive and physical function of each participant during old age, structure and pathology of the brain can be related to early and middle0life risk factors and to late life cognitive and physical function, wide ranges in function and health provide a unique opportunity to better understand the biological and social substrates of severe debility at one end of the continuum and vital, health aging at the other end.