BIO120H1 Chapter Notes - Chapter 4: Genetic Drift, Electrophoresis, Natural Selection

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11 Dec 2010
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BIO120H1 Full Course Notes
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Classical and balance school: struggle to measure genetic variation: selection experiments, electrophoresis revolution, dna sequencing. genetic variation is the raw material upon which evolution acts. we can study genetic diversity to help understand the processes of evolution. The rate of increase in fitness of a population at any time is equal to its genetic variance in fitness at that time. What factors influence patterns of genetic diversity: mutation, random genetic drift, recombination, natural selection, migration. Polymorphism (p) - proportion of gene loci that are polymorphic www. notesolution. com. Muller working with fruit fly mutants: balance model, developed largely by population and ecological geneticists, t. dobzhansky and e. b. Maintenance of genetic variation: mutation-selection balance, diverse selective forces favouring diversity, mutation-selection balance www. notesolution. com. heterozygote advantage, frequency-dependent selection, fitness varies in space and time. Classical school: thomas h. morgan (1866-1945), herman j. muller (1890-1967) Balance school: bernard (h. b. d. ) kettlewell, e. b. Early quantitative genetic evidence for the existence of genetic variation:

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