PSYC 3410 Lecture Notes - Corticotropin-Releasing Hormone, Helicobacter Pylori, Adaptive Immune System

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Stress: coordinated serious of responses to an actual or potential aversive stimulus (physical, social, cognitive, immune) which typically includes alterations in neuroendocrine and autonomic functions with complex changes in behavior. Experience of stress is common to all organisms. Influenced by ones experience, genetics, behavior (individual difference) Repeated: many times, with stress free gaps. Adaptive functions to return body back to normal homeostasis. Hypothalamus paraventricular nucleus (pvn: corticotropin-releasing hormone (crh) or corticotropin releasing factor (crf) When we have stress response our body becomes activated so this deals with it. Note = feedback loop: cortisol itself feeds back to the brain and therefore inhibits the whole system. One being the anterior pituitary system ^ (medial) ** there are images in slides online of both systems. Hippocampus had highest expression of cortisol in the brain it responds to high levels of glucocorticoids and therefore inhibits the system. ** different images show different parts of the brain and their significance.

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