Chemistry 2223B Lecture Notes - Cell Nucleus, Human Genome Project, Netropsin
16 Apr 2014
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Chemistry 2223b winter 2013 14 western university. This chapter focuses on some of the biological and chemical aspects of nucleic acids, specifically dna. We will examine its properties, sequencing, and laboratory synthesis. Background material that is important includes: alcohols, amines, strengths of acids, substitution and elimination reactions, structure and composition of nucleic acids, nucleobases. N atoms 1 and 9, in the pyrimidines and purines respectively, are used to form. The structures shown are the predominant tautomers. When watson and crick worked on dna structure, their work was hindered because the structures found in old textbooks were of the improper tautomers. Nucleosides are the bases attached to sugars (ribose in rna, 2-deoxyribose in. Nucleotides are composed of nucleosides and one or more phosphates. Phosphates can be attached to one or more of the oh groups (2", 3", 5"). The prime refers to the numbering of the sugar. The pka1 of each phosphate group is < 5.
