BIOL 1000 Chapter Notes - Chapter 5: Peripheral Membrane Protein, Integral Membrane Protein, Lipid Bilayer

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21 Apr 2014
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Cystic fibrosis- caused by mutation of a gene in the cystic fibrosis transmembrane conductance regulator(cftr) Cftr is a transport pump which pumps chloride ions out of the cells in the lungs and intestinal tract. The development of the plasma membrane is an important part of evolution of the cell. Fluid mosaic model- model used to view the membrane structure. Membranes are composed of fluid lipid molecules where proteins are embedded and float freely. Many types of proteins along the plasma membrane protein to lipid ratio in membranes vary on the type of membrane. Membrane asymmetry- each side of the lipid bilayer have different components and proteins. Receptor proteins- found outside of plasma membrane, proteins bind to receptor protein which causes change in proteins on the other side of the membrane. Lipids are the foundation of all biological membranes. Phospholipids are all amphipathic- region where it is hydrophobic and hydrophilic. Hydrophobic region is non polar, contains fatty acids.

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