KINE 1020 Lecture Notes - Macrophage

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Inflammatory response: following injury or infection inflammation occurs, mast cells produce histamine, histamine causes blood vessels to dilate and fluid to accumulate leading to swelling, asthma histamine response, heat, redness, swelling, macrophages (big eaters) and neutrophils (kill viruses/ bacteria) attack the infection, pus (collection of dead wbc and debris) The immune system: two kinds of responses, innate, acquired , both recognize the invader based on the invaders antigens, antigen a marker on the surface of a foreign substance that the immune system recognizes as nonself that triggers the immune response, h"s and n"s hold the antigens, several cells respond. Acquired immunity: active own antibodies, natural exposure to infectious agents, artificial immunization, passive ready made antibodies (mothers breast milk, natural maternal antibodies, artificial from other sources, natural killer cell kill cancer cells (mutations, adaptive immunity (slow, b cells produce antibodies after exposure to first viral infection.

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