CHEM 1004 Chapter Notes - Chapter 4: Alcohol Dehydrogenase, Barbiturate, Central Nervous System Depression

• School: Carleton University
• Department: Chemistry
• Course: CHEM 1004
• Professor: Gerald Buchanan

Document Summary

Chapter 4 - what happens to the drugs after taken. Ways of administering drugs: oral ingestion - expected to disintegrate in the stomach and get absorbed in the bloodstream from the stomach or small intestine. Some drugs are designed not to dissolve in the bloodstream (aspirin) or some have to be taken with food (antibiotics) to avoid irritation of the stomach (internal bleeding). A disadvantage is sometime the drug is destroyed by the stomach acid before it is absorbed. Inhaled - rapidly absorbed because of the number of blood vessels in the lungs and nasal region. Nasal decongestants shrink nasal membrane and some proteins can be inhaled in the form of an aerosol spray. Disadvantage: possible drug induced irritation of the mucous membrane. 2: paternal(injected) - hyperdermic injection into muscle, veins, beneath skin, etc. Advantage: rapid access to bloodstream therefore rapid action, and can be stopped if necessary. Best for potent drugs which are taken for long periods of time.